A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity

Nature, Published online: 04 November 2026; doi:10.1038/s41586-026-11234-8 A deep single-cell and spatial multi-omic atlas of human glioblastoma is generated, pairing transcriptomic, epigenomic and genomic profiling, and tracing glioblastoma tumour heterogeneity to a stereotyped and spatially…

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