Photolabile oligonucleotides with topological light gradients enable spatially resolved single-cell transcriptomics and epigenomics

T1Covered by 1 source · first reported by Nature / Science / Nature Biotechnology at 25 Sept, 00:00 UTC

Nature Biotechnology, Published online: 25 September 2026; doi:10.1038/s41587-026-03328-5 A photolabile oligonucleotide system enables spatially resolved single-cell measurements to show how the epigenome regulates gene expression.

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• T1Photolabile oligonucleotides with topological light gradients enable spatially resolved single-cell transcriptomics and epigenomicsNature / Science / Nature Biotechnology25 Sept, 00:00