5-oxoETE links redox control of epithelial damage detection and resilience

T1Covered by 1 source · first reported by Nature / Science / Nature Biotechnology at 07 Oct, 00:00 UTC

Nature, Published online: 07 October 2026; doi:10.1038/s41586-026-11121-2 The DHRS7–OXER1 pathway links oxidative stress to immunity and tissue resilience by modulating 5-oxoETE via NADP+–NADPH, activating OXER1 to recruit antimicrobial cells and induce NUDIX enzymes that protect epithelial redox…