Shotgun engineering fires up mammalian metabolic design
Nature Biotechnology, Published online: 06 October 2026; doi:10.1038/s41587-026-03329-4 By testing random combinations of genes at scale, shotgun genetic engineering enables discovery of new productive metabolic pathways in mammalian cells, including solutions for synthesizing two essential amino…
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- T1Shotgun engineering fires up mammalian metabolic designNature / Science / Nature Biotechnology