TRAM promotes Toll-like-receptor-free myddosome signal transduction

T1Covered by 1 source · first reported by Nature / Science / Nature Biotechnology at 23 Sept, 00:00 UTC

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11052-y TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.

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• T1TRAM promotes Toll-like-receptor-free myddosome signal transductionNature / Science / Nature Biotechnology23 Sept, 00:00